Your privacy, your choice

We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media.

By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with varying standards of data protection.

See our privacy policy for more information on the use of your personal data.

for further information and to change your choices.
Skip to main content

Table 5 Linear discriminant analysis to classify subjects according to their relative pattern of perfusion

From: Brain perfusion in dementia with Lewy bodies and Alzheimer’s disease: an arterial spin labeling MRI study on prodromal and mild dementia stages

Contrast

Regions of interest

Coefficient

Constant

Sensitivity

Specificity

Pro DLB vs HC

Middle temporal (R)

5.5

–24.1

87

90

 

Anterior insula/inferior frontal (R)

9.2

   
 

Superior parietal (R)

8.1

   
 

Superior orbitofrontal (R)

5.1

   
 

Superior frontal (L)

–5.9

   

Mild DLB vs HC

Caudate nucleus (LR)

19.8

–38.5

94

95

 

Middle temporal (R)

13.3

   
 

Anterior insula/inferior frontal (R)

4.8

   
 

Anterior insula (L)

8.4

   

Mild DLB vs mild AD

Superior temporal (R)

9.2

–12.5

100

96

 

Caudate nucleus (L)

5.1

   
 

Inferior frontal (L)

9.4

   
 

Precuneus (LR)

–2.8

   
 

Supramarginal (L)

–12.8

   
  1. Coefficients are mean coefficients (leave-one-out cross-validation) corrected for age and gender. As an example, to distinguish mild DLB from HC: Classification = constant + mean perfusion in bilateral caudate nucleus × 19.8 + mean perfusion in right middle temporal gyrus × 13.3 + mean perfusion in right anterior insula × 4.8 + mean perfusion in left anterior insula × 8.4 AD Alzheimer’s disease, DLB dementia with Lewy bodies, HC healthy (elderly) controls, L left hemisphere, R right hemisphere
Back to article page

Alzheimer's Research & Therapy

ISSN: 1758-9193