Figure 2

Change from baseline in Severe Impairment Battery subdomain scores at week 24 (last observation carried forward). *P <0.001, †P <0.05, ‡ P <0.01. (A) Overall ITT population (MMSE 0 to 20). (B). MMSE 0 to 16. ITT, intent to treat; MMSE, Mini-Mental State Examination; LS, least squares.