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Figure 4 | Alzheimer's Research & Therapy

Figure 4

From: Fluid biomarkers for diagnosing dementia: rationale and the Canadian Consensus on Diagnosis and Treatment of Dementia recommendations for Canadian physicians

Figure 4

Dynamic biomarkers of Alzheimer's disease pathological cascade. The dynamic biomarkers of Alzheimer's disease pathological cascade, as proposed by Jack and collaborators. This model predicts a preclinical and mild cognitive impairment (MCI) stage of Alzheimer's disease (AD) characterized by predominance of amyloid pathology and a dementia phase characterized by amyloid pathology, neurodegenerative changes and subclinical cognitive impairment. Adapted from [4].

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Alzheimer's Research & Therapy

ISSN: 1758-9193