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Figure 1 | Alzheimer's Research & Therapy

Figure 1

From: β-amyloid deposition is shifted to the vasculature and memory impairment is exacerbated when hyperhomocysteinemia is induced in APP/PS1 transgenic mice

Figure 1

Cognitive deficits are additive when hyperhomocysteinemia is induced in APP/PS1 transgenic mice. (A) Two-day radial arm water maze data are graphed. The mean number of errors per trial were calculated for blocks 1 to 10 (each block comprised three trials). Asterisks indicate significant differences for hyperhomocysteinemia (HHcy) wild-type (WT) mice (n = 16), APP/PS1 control mice (n = 20) and HHcy APP/PS1 mice (n = 20) compared to WT control mice (n = 16). **P < 0.01. (B) Final block data only are graphed (block 10). Asterisks indicate significance compared to WT controls. **P < 0.01.

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Alzheimer's Research & Therapy

ISSN: 1758-9193