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Figure 4 | Alzheimer's Research & Therapy

Figure 4

From: Molecular imaging in Alzheimer's disease: new perspectives on biomarkers for early diagnosis and drug development

Figure 4

Multi-tracer positron emission tomography concept to study pathological and functional processes in the brain. Multi-positron emission tomography tracer concept applied in drug trials combined with atrophy studies (magnetic resonance imaging (MRI)), cerebrospinal fluid (CSF) biomarkers and cognitive testing. 11C-PMP, acetylcholinesterase; 11C-PIB, amyloid; 11C-deprenyl, astrocytosis; 11C-nicotine, nicotinic receptors; 18F-FDG, 2-[18F]-fluoro-2-deoxy-D-glucose metabolism. Red, high activity; yellow, medium activity; blue, low activity.

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