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Table 1 Characteristics of the sample a

From: Total testosterone and neuropsychiatric symptoms in elderly men with Alzheimer’s disease

 

Total sample

Low testosterone

Borderline/Normal testosterone

P -value

( N  = 87)

( n  = 44)

( n  = 43)

Age, yr

75.67 (8.033)

77.24 (7.845)

74.14 (8.008)

0.075

Education level, yr

13.44 (4.324)

14.14 (3.771)

12.74 (4.746)

0.137

MMSE score

20.07 (6.789)

20.45 (5.584)

19.70 (7.839)

0.611

CDR-Global score

1.10 (.727)

1.08 (.698)

1.12 (0.762)

0.836

CDR-SOB score

6.62 (4.474)

6.38 (4.019)

6.86 (4.914)

0.624

NPI total

4.15 (2.888)

3.619 (2.408)

4.674 (3.235)

0.092

Testosterone, ng/ml

2.49 (1.046)

2.11 (.804)

3.94 (0.348)

0.000*

APOE ε4 carriers/noncarriers

54%/46%

53%/47%

54%/46%

0.909

Hyperlipidemia

65%

60%

68%

0.455

Hypertension

64%

68%

61%

0.527

Diabetes

17%

17%

17%

0.963

Obesity

19%

14%

24%

0.239

  1. aAPOE ε4, Apolipoprotein E ε4; CDR, Clinical Dementia Rating; MMSE, Mini Mental State Examination; NPI, Neuropsychiatric Inventory; SOB, Sum of Boxes. Data presented are mean (standard deviation) or percent values. *Significant P < 0.05.
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Alzheimer's Research & Therapy

ISSN: 1758-9193