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Table 2 Significant changes in relative perfusion in prodromal patients

From: Brain perfusion in dementia with Lewy bodies and Alzheimer’s disease: an arterial spin labeling MRI study on prodromal and mild dementia stages

Contrast

Region

Laterality

Extent

Coordinates (x,y,z)

Sensitivity

Specificity

Pro DLB < HC

Middle temporal

R

960

38

–58

6

65

76

 

Anterior insula

R

840

36

34

0

74

90

 

Inferior frontal

  
 

Superior parietal

R

648

16

–62

50

80

62

 

Superior orbital

R

336

18

66

–14

54

95

Pro DLB > HC

Superior frontal

L

432

–16

32

38

57

90

Pro AD < HC

Angular

R

1280

42

–54

28

100

95

 

Angular

L

448

–38

60

26

92

76

 

Inferior frontal

R

400

34

38

0

76

92

Pro AD > HC

Supramarginal

L

432

–62

–24

26

69

90

Pro DLB < pro AD

Fusiform

R

984

34

–30

–18

72

69

Pro AD < pro DLB

–

–

–

–

–

–

–

–

  1. Extent is expressed in mm3. Coordinates are in the Montreal National Institute space. Sensitivity and specificity are percentages, relative to DLB identification except for comparison between pro AD and HC AD Alzheimer’s disease, DLB dementia with Lewy bodies, HC healthy (elderly) controls, L left hemisphere, R right hemisphere
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Alzheimer's Research & Therapy

ISSN: 1758-9193