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Fig. 3 | Alzheimer's Research & Therapy

Fig. 3

From: Regional tau deposition measured by [18F]THK5317 positron emission tomography is associated to cognition via glucose metabolism in Alzheimer’s disease

Fig. 3

Causal mediation analyses. The model, presented in (a), assessed the effect of [18F]FDG regional uptake (mediator) on the relationship between [18F]THK5317 retention (independent variable) in the same region and cognitive performance (dependent variable). (b) Results for the four associations tested. Significant results are displayed in bold. ACME average causal mediation effect, ADE average direct effect, FSIQ full-scale intelligence quotient, PET positron emission tomography, RAVL Rey auditory verbal learning test

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Alzheimer's Research & Therapy

ISSN: 1758-9193