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Fig. 4 | Alzheimer's Research & Therapy

Fig. 4

From: LW-AFC, a new formula derived from Liuwei Dihuang decoction, ameliorates behavioral and pathological deterioration via modulating the neuroendocrine-immune system in PrP-hAβPPswe/PS1ΔE9 transgenic mice

Fig. 4

Suppressive effects of LW-AFC on Aβ deposits in the hippocampus of APP/PS1 mice. a Representative immunofluorescence staining images showing amyloid-β (Aβ) deposits (green and indicated by white arrows) in the hippocampus and brain of wild-type (WT) and APP/PS1 (Tgs) mice. Quantification of Aβ deposits in the brain (b) and hippocampus (c) of WT and Tgs mice by Image Pro Plus 6.0 software. Red arrows indicate false positive result of Aβ deposits. The values are mean ± SEM; n = 11–15. **P < 0.01, ***P < 0.001, versus the WT mice by unpaired Student's t test; # P < 0.05, ## P < 0.01, versus the Tgs mice by one-way ANOVA analysis followed by Dunnett’s post hoc test

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Alzheimer's Research & Therapy

ISSN: 1758-9193