Cross-sectional and longitudinal characterization of SCD patients recruited from the community versus from a memory clinic: subjective cognitive decline, psychoaffective factors, cognitive performances, and atrophy progression over time

Table 1 Demographic features of the study populations

	HC	SCD-community	SCD-clinic	ANOVAs, p value
N	28	23	27
Female % (N)	46 (13)	61 (14)	41 (11)	(χ²) NS^¤
Age	72.25 ± 6.33	71.70 ± 6.60	68.30 ± 7.99	0.09
Level of education	11.50 ± 3.64	12.65 ± 4.13	12.85 ± 3.60	0.37
MMSE	28.68 ± 1.09	28.70 ± 1.18	28.70 ± 1.27	0.99
DRS	0.05 ± 1.02	0.08 ± 0.58	−0.12 ± 0.90	0.68
ESR	− 0 ± 0.71	0.01 ± 0.72	− 0.49 ± 1.70	0.18
APOE ε4 (carrier) % (N)	18 (5)	26 (6)	15 (4)	(χ²) NS^¤
Amyloid status (pos) % (N)	22 (6)	45 (10)	33 (9)	(χ²) NS^¤
SUVr	0.97 ± 0.17	1.03 ± 0.18	1.01 ± 0.19	0.46

Values indicate mean ± SD or percentage. When the analyses of variance (ANOVAs) reached significance, Newman-Keuls tests were used. ^¤For gender, HC – SCD-community p = 0.29, HC – SCD-clinic p = 0.71, SCD-community – SCD-clinic p = 0.16; for APOE4 carrier: HC – SCD-community p = 0.49, HC – SCD-clinic p = 0.76, SCD-community – SCD-clinic p = 0.33; for amyloid status: HC – SCD-community 0.09, HC – SCD-clinic p = 0.37, SCD-community – SCD-clinic p = 0.39
Abbreviations: APOE ε4 apolipoprotein E allele 4, DRS w-score of Mattis Dementia Rating Scale, ESR w-score of Encoding, Storage and Recuperation, HC healthy control, MMSE Mini-Mental State Examination, N sample size, NS not significant, pos positive, SCD subjective cognitive decline, SD standardized deviation

ISSN: 1758-9193