Your privacy, your choice

We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media.

By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with varying standards of data protection.

See our privacy policy for more information on the use of your personal data.

for further information and to change your choices.

Skip to main content

Table 1 Characteristics of the included differential miRNA expression studies

From: Prediction of differentially expressed microRNAs in blood as potential biomarkers for Alzheimer’s disease by meta-analysis and adaptive boosting ensemble learning

PubMed ID

Comparison ID

Blood elements

Differential miRNA expression profiling methods (screening method/validation method)

Number of control case

Number of AD case

Number of upregulated miRNA

Number of downregulated miRNA

31857133

31857133_Ser

Serum

qRT-PCR

93

108

 

1

31811079

31811079_Ser

Serum

qRT-PCR

51

32

9

3

31849573

31849573_Pla

Plasma

microRNA microarray/qRT-PCR

31

16

 

2

31809862

31809862_WB

Whole blood

qRT-PCR

214

145

1

1

31766231

31766231_Pla

Plasma

microRNA microarray/qRT-PCR

29

23

1

 

31691877

31691877_Ser

Serum

qRT-PCR

30

30

4

 

31592314

31592314_Pla

Plasma

RNA deep-sequencing/qRT-PCR

11

10

 

6

31572518

31572518_Ser

Serum

qRT-PCR

98

105

 

1

31420923

31420923_Pla

Plasma

qRT-PCR

120

120

 

2

31092279

31092279_Pla

Plasma

qRT-PCR

14

56

3

 

30914454

30914454_Pla

Plasma

qRT-PCR

385

385

 

5

30328325

30328325_Pla

Plasma

qRT-PCR

20

20

1

 

29966198

29966198_Pla

Plasma

qRT-PCR

10

10

2

 

29746584

29746584_Ser

Serum

qRT-PCR

38

47

14

8

29635818

29635818_Pla

Plasma

qRT-PCR

20

20

1

 

29606187

29606187_Ser

Serum

qRT-PCR

107

228

2

1

29036829

29036829_WB

Whole blood

microRNA microarray/qRT-PCR

17

21

 

3

29036818

29036818_Ser_Mild

Serum

RNA deep-sequencing/qRT-PCR

86

31

1

5

29036818_Ser_Mod

Serum

RNA deep-sequencing/qRT-PCR

86

52

3

5

29036818_Ser_Sev

Serum

RNA deep-sequencing/qRT-PCR

86

38

4

5

28934394

28934394_Ser

Serum

microRNA microarray/qRT-PCR

18

11

1

 

28849039

28849039_Ser_Mil

Serum

microRNA microarray/qRT-PCR

30

30

 

1

28849039_Ser_Mod

Serum

microRNA microarray/qRT-PCR

30

30

 

1

28626163

28626163_Ser

Serum

RNA deep-sequencing/qRT-PCR

40

45

5

4

28179587

28179587_Pla_AD2

Plasma

qRT-PCR

9

13

4

3

28179587_Pla_MCI-AD2

Plasma

qRT-PCR

9

8

4

 

28137310

28137310_Ser

Serum

RNA deep-sequencing/qRT-PCR

22

36

 

1

27545218

27545218_Ser

Serum

qRT-PCR

40

48

1

 

27501295

27501295_WB

Whole blood

qRT-PCR

109

172

 

4

27446280

27446280_WB

Whole blood

qRT-PCR

25

25

 

1

27277332

27277332_WB

Whole blood

qRT-PCR

30

30

1

 

27239545

27239545_PBMC

Peripheral blood mononuclear cells

qRT-PCR

36

36

3

 

27027823

27027823_Ser

Serum

qRT-PCR

62

84

1

3

26973465

26973465_Pla

Plasma

microRNA microarray/qRT-PCR

40

40

 

3

26497032

26497032_PBMC

Peripheral blood mononuclear cells

microRNA microarray/qRT-PCR

41

45

2

1

26078483

26078483_Ser

Serum

RNA deep-sequencing/qRT-PCR

75

79

 

4

25955795

25955795_WB

Whole blood

qRT-PCR

30

30

 

1

25742200

25742200_Pla

Plasma

qRT-PCR

81

97

 

1

25667669

25667669_Ser

Serum

qRT-PCR

42

26

 

1

25152461

25152461_Ser

Serum

microRNA microarray/qRT-PCR

30

38

 

2

24827165

24827165_Pla

Plasma

qRT-PCR

7

7

 

1

 

24827165_Ser

Serum

qRT-PCR

7

7

 

1

24577456

24577456_Ser

Serum

RNA deep-sequencing/qRT-PCR

155

158

 

6

24550773

24550773_Pla

Plasma

qRT-PCR

27

25

1

 

24550773_PBMC

Peripheral blood mononuclear cells

qRT-PCR

27

25

1

 

24157723

24157723_Pla

Plasma

qRT-PCR

10

10

 

2

24139697

24139697_Ser

Serum

qRT-PCR

155

105

1

2

24064186

24064186_PBMC_Mon

Monocytes

qRT-PCR

37

34

1

 

24064186_PBMC_Lym

Lymphocytes

qRT-PCR

37

34

1

 

23922807

23922807_Pla_C2

Plasma

microRNA microarray/qRT-PCR

17

20

 

6

23895045

23895045_WB

Whole blood

RNA deep-sequencing/qRT-PCR

21

94

5

7

23435408

23435408_PBMC

Peripheral blood mononuclear cells

qRT-PCR

25

28

 

1

22155483

22155483_Ser

Serum

qRT-PCR

7

7

 

5

19936094

19936094_PBMC

Peripheral blood mononuclear cells

microRNA microarray/qRT-PCR

5

5

2