Table 1 Demographic information of participants from the ROS/MAP cohort

Female

54 (52.9)

126 (71.2)

449 (64.1)

0.002

Age at death in years ^a

85.0 (78.8–89.0)

90.0 (87.4–90.0)

88.5 (84.1–90.0)

< 0.001

Study

 ROS

53 (52.0)

93 (52.5)

381 (54.4)

 MAP

49 (48.0)

84 (47.5)

320 (45.6)

0.926

Global cognitive Z scores at the last visit ^a

0.10 (-0.25–0.36)

-0.35 (-0.93–0.06)

-0.17 (-0.56–0.19)

< 0.001

Slope of global cognitive Z scores ^a

-0.03 (-0.13 – 0.02)

-0.17 (-0.30 – -0.08)

-0.09 (-0.22 – -0.01)

< 0.001

RNA integrity numbers ^a

7.3 (6.0–8.0)

6.7 (5.4–7.4)

6.9 (5.6–7.7)

0.001

Post-mortem interval in hours ^a

6.3 (4.8–8.6)

5.8 (4.2–8.3)

5.8 (4.3–8.5)

0.124