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Table 1 Baseline cardiovascular risk factors of the study population by cardiovascular risk groups and sex

From: Sex matters in the association between cardiovascular health and incident dementia: evidence from real world data

Variable

Sexa

Exposure groupsb (risk at baseline) n (%); mean [sd]

  

Low CVR

Low-intermediate CVR

High-intermediate CVR

High CVR

Previous vascular disease

N

W

462,824 (83.7)

47,482 (8.6)

13,462 (2.4)

6863 (1.2)

22,415 (4.1)

M

178,757 (48.3)

77,084 (20.8)

38,536 (10.4)

33,745 (9.1)

41,804 (11.3)

Age (year)

W

61.3 [7.2]

63.4 [6.0]

63.8 [5.8]

63.8 [5.3]

66.1 [6.3]

M

58.5 [6.3]

63.2 [6.5]

65.5 [6.2]

67.4 [5.5]

65.0 [6.5]

Total cholesterol (mg/dl)

W

216.5 [34.6]

218.1 [39.0]

216.1 [41.6]

218.9 [41.8]

200.5 [38.9]

M

200.5 [35.6]

210.7 [36.0]

214.6 [35.8]

218.7 [37.7]

182.6 [38.9]

HDL (mg/dl)

W

64.2 [14.1]

48.9 [10.0]

45.1 [8.7]

40.9 [7.8]

56.9 [14.3]

M

54.7 [13.2]

49.7 [11.7]

47.5 [10.5]

44.5 [9.5]

48.1 [12.3]

Systolic blood pressure (mmHg)

W

128.8 [14.1]

142.1 [15.6]

144.9 [16.1]

153.1 [17.3]

133.7 [16.8]

M

128.8 [12.8]

136.1 [14.4]

140.6 [15.1)

145.8 [15.5]

133.7 [16.6]

Hypertension

W

154,958 (33.5)

27,982 (58.9)

9310 (69.2)

5210 (75.9)

15,169 (67.7)

M

50,561 (28.3)

32,211 (41.8)

18,556 (48.2)

18,845 (55.8)

25,215 (60.3)

Smoking

W

32,211 (7.0)

5458 (11.5)

1527 (11.3)

941 (13.7)

1260 (5.6)

M

23,170 (13.0)

20,713 (26.9)

13,854 (36.0)

18,432 (54.6)

9032 (21.6)

Diabetes mellitus, type 2

W

23,583 (5.1)

19,448 (41.0)

10,344 (76.8)

6229 (90.8)

6710 (29.9)

M

17,087 (9.6)

10,198 (13.2)

5758 (14.9)

6036 (17.9)

6990 (16.7)

Alcohol-related disorders

W

2269 (0.5)

300 (0.6)

108 (0.8)

58 (0.9)

172 (0.8)

M

6427 (3.6)

3038 (3.9)

1567 (4.1)

1499 (4.4)

2024 (4.8)

Body mass index (kg/m2)

W

28.6 (5.5)

30.8 (6.0)

32.1 (6.2)

32.8 (6.4)

30.5 (5.9)

M

28.1 (4.7)

28.6 (4.8)

28.8 (4.8)

29.2 (4.9)

29.1 (4.8)

  1. aSex: M, men; W, women
  2. bExposure groups based on cardiovascular risk (CVR) at baseline: low (Framingham-REGICOR < 5%), low-intermediate (5% ≤ Framingham-REGICOR < 7.5%), high-intermediate (7.5% ≤ Framingham-REGICOR < 10%), high (Framingham-REGICOR ≥ 10%), and patients with history of vascular disease before the baseline