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Fig. 2 | Alzheimer's Research & Therapy

Fig. 2

From: A systematic review of progranulin concentrations in biofluids in over 7,000 people—assessing the pathogenicity of GRN mutations and other influencing factors

Fig. 2

A PGRN plasma concentrations in GRN mutation carriers (GRN) and non-mutation carriers (Non-GRN). Cut-off determined using the optimal Youden’s index. B PGRN CSF concentrations in GRN mutation carriers (GRN) and non-mutation carriers (non-GRN). Cut-off determined using the optimal Youden’s index. C Serum PGRN concentrations in both GRN mutation carriers (GRN) and non-mutation carriers (non-GRN). Cut-off determined using the optimal Youden’s index. Error bars indicate standard error of the mean (SEM)

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Alzheimer's Research & Therapy

ISSN: 1758-9193