Table 2 Unadjusted and adjusted mortality hazard ratio and their 95% confidence interval for exposure to anti-dementia drugs among nursing home residents with dementia (entire cohort)

Unadjusted

None (reference)

Cholinesterase inhibitors only

0.874

(0.821 to 0.929)

< 0.001

Memantine only

1.002

(0.938 to 1.069)

0.955

Cholinesterase inhibitors plus memantine

0.784

(0.686 to 0.897)

< 0.001

Adjusted (model 1)*

None (reference)

Cholinesterase inhibitors only

0.826

(0.769 to 0.888)

< 0.001

Memantine only

0.857

(0.795 to 0.923)

< 0.001

Cholinesterase inhibitors plus memantine

0.742

(0.640 to 0.861)

< 0.001

Adjusted (model 2)**

None (reference)

Cholinesterase inhibitors only

0.830

(0.772 to 0.892)

< 0.001

Memantine only

0.877

(0.813 to 0.946)

< 0.001

Cholinesterase inhibitors plus memantine

0.762

(0.657 to 0.885)

< 0.001