Table 5 Biomarker results
0-week | 20-week | Change over 20 weeks | |||||
|---|---|---|---|---|---|---|---|
Biomarker | Control | Intervention | Control | Intervention | Control | Intervention | p-value |
Plasma AB42/40 Ratio | 0.048 | 0.047 | 0.044 | 0.049 | -0.004 | 0.003 | 0.003 |
Phosphorylated Tau181 (pTau181) | 45.32 | 43.57 | 50.72 | 43.74 | 5.40 | 0.17 | 0.209 |
Insulin | 9.50 | 8.68 | 8.21 | 6.77 | -1.30 | -1.92 | 0.048 |
Beta-Hydroxybutyrate (ketones) | 0.11 | 0.09 | 0.06 | 0.11 | -0.05 | 0.02 | 0.021 |
LDL cholesterol | 1.91 | 1.93 | 1.95 | 1.32 | 0.04 | -0.61 | <0.001 |
Glial Fibrillary Acidic Protein (GFAP) | 250.27 | 229.68 | 282.69 | 232.85 | 32.42 | 3.16 | 0.199 |
C-reactive Protein (CRP) | 2.02 | 2.00 | 1.75 | 0.95 | -0.27 | -1.05 | 0.373 |
Serum amyloid A (SAA) | 6.42 | 5.79 | 6.30 | 4.14 | -0.12 | -1.65 | 0.074 |
Glycoprotein acetylation (GlycA) | 0.843 | 0.891 | 0.83 | 0.81 | -0.01 | -0.08 | 0.005 |
Telomere length | 0.774 | 0.799 | 0.776 | 0.814 | 0.002 | 0.015 | 0.287 |