Fig. 3

Neuroimaging studies of the FTD patients with TBK1 and OPTN variants. The upper lane shows the cranial MRI. The atrophic changes in frontotemporal regions are indicated by white arrows. The lower lane shows the 18F-FDG-PET images. The color bar of the 18F-FDG-PET images indicates the corresponding regional standardized uptake value ratios (SUVR)