| Overall | Sporadic FTD | Familial FTD | bvFTD | svPPA | nvPPA | FTD-ALS | FTD-P |
---|---|---|---|---|---|---|---|---|
Cases, n | 261 | 229 (87.7%) | 32 (12.3%) | 185 (70.9%) | 40(15.3%) | 14(5.4%) | 9(3.5%) | 13(5.0%) |
Female, n (%) | 144 (55.2%) | 129 (56.3%) | 15 (46.9%) | 103 (55.7%) | 21 (52.1%) | 8 (57.1%) | 5 (55.6%) | 7 (53.8%) |
Age (years) | 60.2 ± 10.6 | 61.3 ± 10.4 | 54.5 ± 3.0 | 61.7 ± 8.9 | 59.3 ± 4.5 | 59.6 ± 4.1 | 62.8 ± 2.2 | 63.4 ± 2.7 |
AAO (years) | 57.7 ± 10.9 | 58.8 ± 10.1 | 52.6 ± 3.0 | 58.8 ± 8.6 | 57.2 ± 4.5 | 56.6 ± 4.4 | 61.0 ± 2.4 | 59.5 ± 2.8 |
Early-onset n (%) | 237 (90.8%) | 207 (90.4%) | 30 (93.8%) | 169 (91.4%) | 37 (92.5%) | 14 (100%) | 8 (88.9%) | 9 (69.2%) |
Minimum disease durationa (years) | 2.6 ± 1.8 | 2.5 ± 1.8 | 2.0 ± 1.7 | 2.8 ± 1.9 | 2.1 ± 1.6 | 3.1 ± 2.0 | 1.9 ± 1.8 | 3.9 ± 2.2 |
MMSE score | 17.8 ± 6.9 | 18.0 ± 6.6 | 16.8 ± 6.3 | 17.6 ± 6.7 | 15.6 ± 5.2 | 15.4 ± 4.7 | 20.2 ± 3.6 | 18.4 ± 2.3 |
MoCA score | 11.5 ± 6.4 | 12.2 ± 6.1 | 10.5 ± 5.7 | 11.0 ± 6.2 | 9.9 ± 5.6 | 10.5 ± 4.9 | 15.6 ± 4.1 | 12.4 ± 1.8 |
Genetically diagnosed | 61 (23.4%) | 44 (19.2%) | 17 (53.1%) | 42 (22.7%) | 9 (22.5%) | 0 | 4 (44.4%) | 6 (46.2%) |