Effects of time of the day at sampling on CSF and plasma levels of Alzheimer’ disease biomarkers

Table 1 Demographics and clinical characteristics of all subjects

	All subjects	Aβ +	Aβ -	P-value Aβ⁺ vs. Aβ ⁻
N	38	18	20
Age (years)	77 (5.91)	78 (4.41)	76 (6.86)	0.08
Gender (F/M)	16/22	8/10	8/12	0.52
APOE ε4 positivity, n (%)	15 (39)	12 (71)	3 (15)	0.002
MMSE	28 (2.10)	28 (1.84)	29 (2.25)	0.16
Diagnosis
Cognitively Unimpaired Cognitively Impaired	35 3	16 2	19 1	0.32
Kidney Function (eGFR)^a	122.29 (21.54)	119.71 (20.52)	124.57 (23.09)	0.54
BMI^b	26.64 (2.84)	25.86 (2.31)	27.29 (3.13)	0.31

Data shown as mean (SD) unless specified otherwise
Abbreviations: M, male; F, female; APOE, apolipoprotein; MMSE, Mini-Mental State Examination, eGFR, estimated glomerular filtration rate; BMI, Body Mass Index
^a Data was missing in 5 participants (2 Aβ + and 3 Aβ -)
^b Data was missing in 3 participants (2 Aβ + and 1 Aβ-)

ISSN: 1758-9193