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Table 2 Hormone therapy interacts with cortical Aβ and is associated with lower regional tau-PET SUVRs

From: Hormone therapy is associated with lower Alzheimer’s disease tau biomarkers in post-menopausal females -evidence from two independent cohorts

  1. Multivariate linear regression models were performed to understand how the interaction between Aβ and HT influenced regional tau load in the brain. The results showed that HT interacted with neocortical Aβ-PET and is associated with lower tau-PET in Braak ROIs. The findings remained significant after correcting for age, education, APOE ε4 carriage status and clinical diagnosis. Interaction plots are demonstrated on the right side of the table
  2. Abbreviation: HT: hormone therapy; CU: cognitively unimpaired
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Alzheimer's Research & Therapy

ISSN: 1758-9193