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Fig. 1 | Alzheimer's Research & Therapy

Fig. 1

From: Neuropsychiatric symptoms and lifelong mental activities in cerebral amyloid angiopathy – a cross-sectional study

Fig. 1

Mediation model testing indirect effects of lifelong mental activities on cerebral amyloid angiopathy (CAA) severity and neuropsychiatric symptom (NPS) number. CAA total score was the independent, NPS number the dependent variable and the lifetime of experiences questionnaire (LEQ) total score the mediator. Covariates were age, sex, years of education, arterial hypertension, Alzheimer’s disease pathology, apolipoprotein E status. a: effect of CAA severity on LEQ total score (-1.68, 95% confidence interval (CI) -3.24 to -0.12, p = 0.035). b: effect of LEQ total score on NPS number (-0.26, 95% CI -0.05 to -0.002, p = 0.033). c’: direct effect of CAA score on NPS number (0.22, 95% CI 0.04–0.39, p = 0.014). c: total effect of CAA score on NPS number (0.26, 95% CI 0.09–0.44, p = 0.003)

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Alzheimer's Research & Therapy

ISSN: 1758-9193