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Table 2 Description of the study sample – NPS and lifelong mental activities

From: Neuropsychiatric symptoms and lifelong mental activities in cerebral amyloid angiopathy – a cross-sectional study

 

Overall (n = 87)

Cerebral amyloid angiopathy (n = 69)

NC (n = 18)

p-value (p < 0.05) group analysis

p-value subgroup analysis*

ADAS-NC

ADAS-NC9 total number

1 (0–6)

2 (0–6)

0 (0–1)

< 0.001

 

ADAS-NC9 total severity

2 (0–11)

3 (0–11)

0 (0–2)

< 0.001

 

GDS-SF

No depression, n (%)

Minor depressive disorder, n (%)

Major depressive disorder, n (%)

n = 85

56 (65.88)

26 (30.58)

3 (3.52)

n = 67

38 (56.71)

26 (38.80)

3 (4.47)

n = 18

18 (100)

0 (0)

0 (0)

0.001

p < 0.0083

< 0.001

0.002

0.374

LEQ

LEQ YA education

16.50 (7.96)

15.68 (8.20)

19.64 (6.18)

0.009

 

LEQ YA activities

19.18 (3.93)

19.03 (3.84)

19.76 (4.34)

0.797

 

LEQ YA total

36.49 (10.10)

35.47 (10.42)

40.39 (7.87)

0.012

 

LEQ ML occupation

61.58 (22.75)

59.51 (22.79)

69.52 (21.34)

0.098

 

LEQ ML activities

16.78 (3.63)

16.43 (3.61)

18.11 (3.49)

0.047

 

LEQ ML total

34.34 (8.68)

32.90 (8.25)

39.84 (8.28)

0.003

 

LEQ LL specific activities

18.71 (5.00)

17.50 (4.59)

23.35 (3.72)

< 0.001

 

LEQ LL nonspecific activities

14.58 (3.03)

13.93 (2.80)

17.05 (2.64)

< 0.001

 

LEQ LL total

22.39 (5.32)

21.35 (5.20)

26.40 (3.71)

< 0.001

 

LEQ total (cognitive reserve)

93.02 (18.63)

89.47 (18.28)

106.63 (13.08)

< 0.001

 
  1. Note: Values are mean (standard deviation) or median (range) unless otherwise noted. Significant p-values are marked bold. p-values are based on chi-square or Fisher’s exact test (if any cell number was < 5) for categorical variables, and the Mann-Whitney U test for continuous variables. *p-value subgroup analysis is based on post-hoc chi-square testing for multiple comparisons. NPS: neuropsychiatric symptoms. ADAS-NC9: Alzheimer’s Disease Assessment Scale subscale noncognitive with nine items. GDS-SF: Geriatric Depression Scale-Short Form. LEQ: Lifetime of Experiences Questionnaire. YA: young adult. ML: mid-life. LL: late-life