Skip to main content

Table 5 Multivariable-adjusted associations of imaging markers of CAA severity with the number and severity of NPS.

From: Neuropsychiatric symptoms and lifelong mental activities in cerebral amyloid angiopathy – a cross-sectional study

 

Number of NPS

NPS total severity

Incidence rate ratio (95% CI)

p-value

Estimate (95% CI)

p-value

Marker

CSO PVS (category 0–4)

WMH sum (category 0–6)

Lobar CMB count

CSS sum (category 0–4)

CAA score (0–6)

1.12 (0.84 to 1.49)

1.21 (1.05 to 1.39)

1.00 (0.99 to 1.00)

1.02 (0.88 to 1.20)

1.14 (1.01 to 1.27)

0.426

0.006

0.954

0.719

0.022

0.13 (-0.84 to 1.10)

0.63 (0.19 to 1.08)

0.00 (-0.12 to 0.02)

0.28 (-0.35 to 0.92)

0.57 (0.19 to 0.95)

0.791

0.005

0.473

0.373

0.004

  1. Note: Covariates were age, sex, years of education, arterial hypertension, AD pathology, APOE status, and magnetic resonance imaging field strength (3 Tesla or 1.5 Tesla). Significant p-values are marked bold. CSO PVS: centrum semiovale enlarged perivascular spaces. WMH: white matter hyperintensities. CMB: cerebral microbleeds. CSS: cortical superficial siderosis