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Fig. 4 | Alzheimer's Research & Therapy

Fig. 4

From: Choroid plexus volume as a novel candidate neuroimaging marker of the Alzheimer’s continuum

Fig. 4

Receiver operating characteristic curves of four neuroimaging measures for discriminating the cerebral Aβ42 change and distinguishing different stages of the AD continuum. (A) The AUC of ChP volume alone is higher than that of LVV (P = 0.038) and ECT (P = 0.008) alone, and that of combined ChP and hippocampal volume is higher than that of hippocampal volume alone (P = 0.033). However, the combination of four neuroimaging measures (P = 0.443) or that of ChP and hippocampal volume (P = 0.735) does not show significant advantage over ChP volume alone; (B) The AUC of ChP volume alone is higher than those of hippocampal volume (P = 0.009) and LVV (P = 0.031) alone. The AUC of combined ChP and hippocampal volumes is higher than that of hippocampal volume alone (P = 0.009) but not higher than that of ChP volume alone (P = 0.654); (C) The AUC of combined ChP and hippocampal volumes is higher than those of hippocampal volume alone (P = 0.008) and ChP volume alone(P < 0.001); (D) The AUC of combined ChP and hippocampal volumes is higher than those of hippocampal volume alone (P = 0.004) and ChP volume alone (P = 0.001)

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