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Table 2 Overview of HDI and MEDAS score for all study groups and the pooled intervention group

From: Nutrition guidance within a multimodal intervention improves diet quality in prodromal Alzheimer’s disease: Multimodal Preventive Trial for Alzheimer’s Disease (MIND-ADmini)

  

Control (n = 28)

Lifestyle Intervention (n = 28)

P*

Lifestyle + Medical Food (n = 29)

P*

Pooled Intervention Groups (n = 57)

P*

HDI

 Median (IQR)

Baseline

59 (52–65)

50 (42–58)

 

58.0 (51–64)

 

56.0 (48–63)

 

 Mean Δ (SE)

6-m

-2.4 (1.6)

1.9 (1.5)

0.052

3.1 (1.2)*

0.040

2.5 (1.0)*

0.027

MEDAS

 Median (IQR)

Baseline

6.0 (4–7)

6.0 (5–8)

 

5.5 (5–7)

 

6.0 (5–8)

 

 Mean Δ (SE)

Δ 6-m

-0.4 (0.3)

0.5 (0.4)*

0.045

1.0 (0.4)*

0.007

0.7 (0.3)*

0.007

  1. Mixed linear regression for between group differences and mean change from baseline. Lower/upper limit: HDI 0–97, MEDAS score 0–14
  2. * P < 0.05 for change between intervention groups and control group
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Alzheimer's Research & Therapy

ISSN: 1758-9193