Quantitative transport mapping of multi-delay arterial spin labeling MRI detects early blood perfusion alterations in Alzheimer’s disease

Table 3 Correlation of CBF and QTM values with cognition in cortical GM and hippocampus. The top panel is for the whole group and the bottom panel is for non-AD groups

	MMSE		Immediate recall		Delay recall		TMT-A		TMT-B
	r	p	r	p	r	p	r	p	r	p	r	p
Relationship between CBF (ml/100 g/min) and cognition
GM	0.29	< 0.01	0.27	< 0.01	0.28	< 0.01	-0.22	< 0.05	-0.35	< 0.001	0.26	< 0.01
Hippo	0.26	< 0.01	0.29	< 0.01	0.33	< 0.01	-0.15	0.10	-0.29	< 0.01	0.25	< 0.01
Relationship between QTM velocity (mm/sec) and cognition
GM	0.27	< 0.01	0.26	< 0.01	0.21	< 0.05	-0.15	0.09	-0.19	< 0.05	0.23	< 0.01
Hippo	0.29	< 0.01	0.28	< 0.01	0.25	< 0.01	-0.10	0.28	-0.21	< 0.05	0.25	< 0.01
Relationship between CBF (ml/100 g/min) and cognition excludes the AD group
GM	0.02	0.86	0.16	0.12	0.17	0.09	0.01	0.92	-0.24	< 0.05	0.16	0.12
Hippo	0.01	0.97	0.16	0.11	0.25	< 0.05	0.05	0.64	-0.20	0.06	0.18	0.08
Relationship between QTM velocity (mm/sec) and cognition excludes the AD group
GM	0	1	0.17	0.09	0.08	0.42	0.05	0.64	-0.17	0.09	0.11	0.28
Hippo	0.09	0.35	0.21	< 0.05	0.16	0.11	0	0.92	-0.20	< 0.05	0.14	0.16

ISSN: 1758-9193