Fig. 1

Example of the combined visual (upper panel, axial and coronal slices of brain 18F-FDG PET images) and semiquantitative (lower panel, with hypometabolisms in green projected on axial MR slices on the left and hypometabolisms in blue on a 3D volume rendered on the right) analysis for a 65-year-old male patient (initially diagnosed with MCI); these results were consistent with Alzheimer’s disease. The final diagnosis in the National Alzheimer’s database was Alzheimer’s disease and conversion to dementia after 31.5 months