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Fig. 2 | Alzheimer's Research & Therapy

Fig. 2

From: Effects of strategic white matter hyperintensities of cholinergic pathways on basal forebrain volume in patients with amyloid-negative neurocognitive disorders

Fig. 2

Representative fluid-attenuated inversion recovery (FLAIR) images of patients in each CHIPS tertile group. In Panels A through C, the top row of each panel is the original MRI image, and the bottom row is the image with the region of interest added. Colored lines represent the medial (blue) and lateral (red) cholinergic pathways. The Montreal Neurological Institute (MNI) z-coordinates of the associated index images are about − 1, 10, 25, and 37. Panels A through C shows representative FLAIR images of each CHIPS tertile group at the low external capsule, high external capsule, corona radiata, and centrum semiovale levels, from left to right. A represents CHIPSt1 with a CHIPS score of 7, C represents CHIPSt2 with a CHIPS score of 17, and D represents CHIPSt3 with a CHIPS score 72

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Alzheimer's Research & Therapy

ISSN: 1758-9193