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Fig. 2 | Alzheimer's Research & Therapy

Fig. 2

From: Comparing regional brain uptake of incretin receptor agonists after intranasal delivery in CD-1 mice and the APP/PS1 mouse model of Alzheimer’s disease

Fig. 2

Comparison of whole brain uptake of radiolabeled IRAs in CD-1 mice 30 min after intranasal (IN) or intravenous (IV) delivery. The IN data (open bars) are from the present study, limited to male mice. The IV data (closed bars) are from our previous studies in male mice [65, 66]. ANOVA was statistically significant due to IRA (p = 0.0023), route of delivery (p < 0.0001), and there was an IRA by route interaction (p = 0.0192). Route post hoc differences are as marked, *p < 0.05. n = 2/IRA IV, n = 4/IRA IN

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Alzheimer's Research & Therapy

ISSN: 1758-9193