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Fig. 5 | Alzheimer's Research & Therapy

Fig. 5

From: Comparing regional brain uptake of incretin receptor agonists after intranasal delivery in CD-1 mice and the APP/PS1 mouse model of Alzheimer’s disease

Fig. 5

Dulaglutide distribution in APP/PS1 male mice and WT littermate males following IN delivery. Distribution in (A) whole brain, (B) olfactory bulb, (C) neocortex (frontal + parietal + occipital), (D) hippocampus, (E) hypothalamus, and (F) serum. ANOVA time *p < 0.05 for all regions; post hoc: bp<0.05 vs. 5 min only in WT; there was no effect due to the AD transgene. See Supp Table 2 for additional statistical differences. n = 3–4/time point/genotype

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Alzheimer's Research & Therapy

ISSN: 1758-9193