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Fig. 8 | Alzheimer's Research & Therapy

Fig. 8

From: Comparing regional brain uptake of incretin receptor agonists after intranasal delivery in CD-1 mice and the APP/PS1 mouse model of Alzheimer’s disease

Fig. 8

DA4-JC distribution in APP/PS1 female mice and WT littermate females following IN delivery. Distribution in (A) whole brain, (B) olfactory bulb, (C) neocortex (frontal + parietal + occipital), (D) hippocampus, (E) hypothalamus, and (F) serum. ANOVA time *p < 0.05 for hypothalamus; ANOVA genotype *p < 0.05 for whole brain (neocortex p = 0.096, serum p = 0.064); post hoc: #p < 0.05 as marked. See Supp Table 3 for additional statistical differences. n = 1–4/time point/genotype

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Alzheimer's Research & Therapy

ISSN: 1758-9193