Digital remote assessment of speech acoustics in cognitively unimpaired adults: feasibility, reliability and associations with amyloid pathology

Table 2 Participant characteristics

	Total group (N = 50)	Amyloid-beta positive (n = 23)	Amyloid-beta negative (n = 27)	p-value
Age, years, mean ± SD	68.4 ± 6.2	69.6 ± 6.3	67.3 ± 6.0	0.193^a
Female, n (%)	29 (58.0)	13 (56.5)	16 (59.3)	0.845^d
Education, years, mean ± SD	15.3 ± 3.8	15.2 ± 4.6	15.3 ± 3.0	0.944^b
Cohort				0.233^d
AMYPAD PNHS, n (%)	34 (68.0)	13 (56.5)	21 (77.8)
SCIENCe, n (%)	12 (24.0)	8 (34.8)	4 (14.8)
ADC, n (%)	4 (8.0)	2 (8.7)	2 (7.4)
Amyloid-beta biomarkers				0.508^d
Cerebrospinal Fluid, n (%)	5 (10.0)	3 (13.0)	2 (7.4)
Positron Emission Tomography, n (%)	45 (90.0)	20 (87.0)	25 (92.6)
Mini-Mental State Examination, mean ± SD	29.2 ± 1.0	28.8 ± 1.1	29.5 ± 0.7	0.012^c

Note Data are depicted as mean ± standard deviation (SD) unless otherwise indicated; Differences between amyloid-beta positive individuals and amyloid-beta negative individuals are tested . ^aStudent t-test, ^bWelch t-test, ^c Wilcoxon test, ^dChi-Square test

ISSN: 1758-9193