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Table 1 Demographic and clinical characteristics of study participants

From: Association of outer retinal and choroidal alterations with neuroimaging and clinical features in posterior cortical atrophy

Characteristic

Participants

with PCA

Healthy control participants

P-value

Number (eyes)

28(53)

56(112)

 

Sex, female/male

19(9)

35(21)

0.629

Age, mean (SD), y

60.21 ± 7.38

60.11 ± 7.92

0.687

Educational level, mean (SD), y

10.68 ± 4.23

13.61 ± 3.88

0.804

MoCA score

10.07 ± 5.62

27.25 ± 0.81

< 0.001

MMSE score

15.36 ± 5.58

27.82 ± 0.88

< 0.001

CDR score

   

 CDR-G score

0.86 ± 0.41

0

< 0.001

 CDR-SB score

5.05 ± 2.43

0

< 0.001

Aβ positivity, n (%)

28(100%)

  

APOE genotype

   

 ε2/ε3

1

  

 ε2/ε4

2

  

 ε3/ε3

12

  

 ε3/ε4

8

  

 ε4/ε4

1

  

 unclear

4

  
  1. Abbreviations: PCA, Posterior cortical atrophy; SD, Standard deviation; MoCA, Montreal Cognitive Assessment; MMSE, Mini-Mental State Examination; CDR, Clinical Dementia Rating; CDR-G, Clinical Dementia Rating-Global; CDR-SB, Clinical Dementia Rating -Sum of Boxes; Aβ, amyloid β; APOE, apolipoprotein E
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Alzheimer's Research & Therapy

ISSN: 1758-9193