Association of outer retinal and choroidal alterations with neuroimaging and clinical features in posterior cortical atrophy

Table 3 Association of outer retinal and choroidal structural and flow parameters with PCA clinical features

Parameters	MOCA		MMSE		CDR-G		CDR-SB
Parameters	r	P-value^*	r	P-value^*	r	P-value^*	r	P-value^*
ORT
0–1 mm	-0.030	0.883	0.302	0.134	0.009	0.963	0.020	0.924
1–3 mm	0.101	0.622	0.202	0.322	-0.204	0.319	-0.255	0.209
3–6 mm	0.091	0.660	0.000	0.999	-0.193	0.345	-0.243	0.232
CRT
0–1 mm	0.423	0.031	0.348	0.082	-0.368	0.064	-0.284	0.159
1–3 mm	0.381	0.055	0.277	0.170	-0.374	0.060	-0.263	0.194
3–6 mm	0.364	0.068	0.193	0.346	-0.352	0.078	-0.256	0.208
Choriocapillaris VD
0–1 mm	-0.126	0.540	-0.091	0.660	0.026	0.898	-0.032	0.877
1–3 mm	-0.035	0.864	-0.121	0.555	-0.081	0.693	-0.055	0.790
3–6 mm	0.362	0.069	0.171	0.403	-0.163	0.426	-0.101	0.623
CVI
0–1 mm	0.069	0.738	0.311	0.123	-0.120	0.558	-0.258	0.204
1–3 mm	-0.036	0.863	0.160	0.435	0.009	0.963	-0.126	0.539
3–6 mm	0.003	0.990	0.116	0.573	-0.108	0.599	-0.215	0.292
CVV
0–1 mm	0.433	0.027	0.485	0.012	-0.469	0.016	-0.446	0.022
1–3 mm	0.386	0.051	0.376	0.059	-0.427	0.030	-0.379	0.056
3–6 mm	0.330	0.100	0.251	0.216	-0.361	0.070	-0.338	0.091

Abbreviations: PCA, Posterior cortical atrophy; ORT, outer retina thickness; CRT, choroid thickness; VD vessel density; CVI, choroidal vascular index; CVV, choroidal vascular volume; CDR-G, Clinical Dementia Rating-Global score; CDR-SB, Clinical Dementia Rating-Sum of Boxes; MMSE, Mini-Mental State Examination; MoCA, Montreal Cognitive Assessment
^*P value was adjusted for the age and sex

ISSN: 1758-9193