Table 2 Multivariate mixed-effects model analyses of the temporal associations between executive function/memory function and risk factors
From: Risk factors for cognitive decline in non-demented elders with amyloid-beta positivity
Factors | Executive function | Memory function | ||||||
|---|---|---|---|---|---|---|---|---|
β | SE | 95% Cl | p | β | SE | 95% Cl | p | |
Body weight (kg) | 0.01 | 0.01 | [-0.01, 0.02] | 0.4553 | 0.01 | 0.01 | [0.00, 0.03] | 0.1114 |
BMI (≥ 25 kg/m2) | 0.01 | 0.01 | [0.00, 0.02] | 0.1637 | 0.02 | 0.01 | [0.00, 0.04] | 0.0367 |
Diastolic pressure (mmHg) | 0.01 | 0.01 | [0.00, 0.03] | 0.0440 | 0.01 | 0.01 | [-0.01, 0.02] | 0.5205 |
Race (ref: White) | ||||||||
Asian (yes) | 0.06 | 0.04 | [-0.02, 0.13] | 0.1330 | 0.01 | 0.05 | [-0.07, 0.10] | 0.7585 |
Black (yes) | 0.04 | 0.07 | [-0.09, 0.17] | 0.5672 | <-0.01 | 0.10 | [-0.19, 0.19] | 0.9968 |
More than one (yes) | 0.07 | 0.05 | [-0.03, 0.17] | 0.1594 | 0.07 | 0.05 | [-0.03, 0.17] | 0.1528 |
Parental dementia (yes) | < 0.01 | 0.01 | [-0.01, 0.02] | 0.5658 | 0.01 | 0.01 | [-0.01, 0.02] | 0.5731 |
Drug abuse (yes) | < 0.01 | 0.01 | [-0.02, 0.02] | 0.9423 | -0.02 | 0.01 | [-0.04, 0.00] | 0.0136 |
Marital Status (ref: Married) | ||||||||
Divorced | <-0.01 | 0.03 | [-0.05, 0.05] | 0.9483 | 0.04 | 0.03 | [-0.02, 0.10] | 0.1758 |
Widowed | -0.02 | 0.02 | [-0.06, 0.03] | 0.4332 | 0.01 | 0.03 | [-0.05, 0.06] | 0.7974 |
Never married | 0.05 | 0.04 | [-0.02, 0.12] | 0.1417 | 0.03 | 0.04 | [-0.05, 0.11] | 0.4229 |
Retired (yes) | -0.02 | 0.01 | [-0.03, 0.00] | 0.0506 | -0.01 | 0.01 | [-0.03, 0.00] | 0.1406 |
Hypertension (yes) | 0.01 | 0.01 | [0.00, 0.03] | 0.0576 | <-0.01 | 0.01 | [-0.02, 0.01] | 0.7536 |
Psychiatric diseases (yes) | <-0.01 | 0.01 | [-0.01, 0.01] | 0.9450 | -0.01 | 0.01 | [-0.02, 0.01] | 0.4401 |
Cardiovascular diseases (yes) | 0.01 | 0.01 | [0.00, 0.02] | 0.1744 | < 0.01 | 0.01 | [-0.02, 0.02] | 0.8774 |
Dermatologic-Connective Tissue diseases (yes) | 0.02 | 0.01 | [0.00, 0.03] | 0.0085 | 0.01 | 0.01 | [-0.01, 0.02] | 0.4292 |
Musculoskeletal diseases (yes) | 0.01 | 0.01 | [-0.01, 0.02] | 0.4430 | -0.02 | 0.01 | [-0.04, 0.00] | 0.0368 |
Hematopoietic-Lymphatic diseases (yes) | 0.01 | 0.01 | [0.00, 0.02] | 0.1382 | 0.01 | 0.01 | [-0.01, 0.03] | 0.1955 |
Urinary disease (yes) | <-0.01 | 0.01 | [-0.01, 0.01] | 0.9301 | -0.01 | 0.01 | [-0.03, 0.01] | 0.3469 |
Allergies or Drug Sensitivities (yes) | <-0.01 | 0.01 | [-0.02, 0.01] | 0.8407 | -0.01 | 0.01 | [-0.02, 0.01] | 0.3987 |
Major Surgical Procedures (yes) | 0.01 | 0.01 | [-0.01, 0.02] | 0.3284 | 0.01 | 0.01 | [-0.01, 0.03] | 0.1771 |
Parkinsonism (yes) | -0.01 | 0.01 | [-0.03, 0.01] | 0.3313 | -0.02 | 0.01 | [-0.04, 0.00] | 0.0129 |
Geriatric Depression Scale | -0.03 | 0.01 | [-0.04, -0.02] | < 0.0001 | -0.02 | 0.01 | [-0.04, 0.00] | 0.0116 |
Hachinski ischemic Scores | 0.01 | 0.01 | [0.00, 0.03] | 0.0539 | -0.01 | 0.01 | [-0.03, 0.01] | 0.2312 |