Table 3 Multivariate mixed-effects model analyses of the temporal associations between MMSE/MoCA and risk factors
From: Risk factors for cognitive decline in non-demented elders with amyloid-beta positivity
Factors | MMSE | MoCA | ||||||
|---|---|---|---|---|---|---|---|---|
β | SE | 95% Cl | p | β | SE | 95% Cl | p | |
Body weight (kg) | 0.01 | 0.01 | [-0.01, 0.03] | 0.2170 | 0.01 | 0.01 | [-0.01, 0.02] | 0.4318 |
BMI (≥ 25 kg/m2) | 0.01 | 0.01 | [-0.01, 0.04] | 0.1986 | 0.02 | 0.01 | [0.00, 0.04] | 0.0306 |
Diastolic pressure (mmHg) | 0.01 | 0.01 | [-0.01, 0.03] | 0.3055 | 0.02 | 0.01 | [0.00, 0.04] | 0.0214 |
Race (ref: White) | ||||||||
Asian (yes) | 0.03 | 0.06 | [-0.08, 0.14] | 0.5754 | -0.02 | 0.05 | [-0.11, 0.08] | 0.7280 |
Black (yes) | <-0.01 | 0.13 | [-0.25, 0.24] | 0.9735 | 0.01 | 0.09 | [-0.16, 0.18] | 0.9302 |
More than one (yes) | 0.07 | 0.06 | [-0.05, 0.18] | 0.2778 | 0.10 | 0.05 | [0.00, 0.21] | 0.0585 |
Parental dementia (yes) | 0.01 | 0.01 | [-0.01, 0.03] | 0.4393 | < 0.01 | 0.01 | [-0.01, 0.02] | 0.6298 |
Drug abuse (yes) | <-0.01 | 0.01 | [-0.03, 0.02] | 0.6438 | -0.02 | 0.01 | [-0.04, -0.01] | 0.0113 |
Marital Status (ref: Married) | ||||||||
Divorced | 0.05 | 0.03 | [-0.01, 0.12] | 0.1329 | < 0.01 | 0.03 | [-0.06, 0.06] | 0.9595 |
Widowed | 0.01 | 0.03 | [-0.05, 0.08] | 0.7045 | 0.03 | 0.03 | [-0.03, 0.08] | 0.3165 |
Never married | 0.04 | 0.05 | [-0.05, 0.13] | 0.3920 | 0.04 | 0.04 | [-0.04, 0.12] | 0.2939 |
Retired (yes) | -0.03 | 0.01 | [-0.05, -0.01] | 0.0048 | -0.03 | 0.01 | [-0.04, -0.01] | 0.0025 |
Hypertension (yes) | < 0.01 | 0.01 | [-0.02, 0.02] | 0.8495 | 0.01 | 0.01 | [0.00, 0.03] | 0.1505 |
Psychiatric diseases (yes) | -0.01 | 0.01 | [-0.04, 0.01] | 0.1599 | < 0.01 | 0.01 | [-0.01, 0.02] | 0.7046 |
Cardiovascular diseases (yes) | < 0.01 | 0.01 | [-0.02, 0.02] | 0.8146 | 0.02 | 0.01 | [0.00, 0.03] | 0.0815 |
Dermatologic-Connective Tissue diseases (yes) | < 0.01 | 0.01 | [-0.02, 0.02] | 0.6984 | <-0.01 | 0.01 | [-0.02, 0.02] | 0.9776 |
Musculoskeletal diseases (yes) | -0.01 | 0.01 | [-0.03, 0.01] | 0.3257 | -0.01 | 0.01 | [-0.03, 0.01] | 0.3376 |
Hematopoietic-Lymphatic diseases (yes) | <-0.01 | 0.01 | [-0.02, 0.02] | 0.7390 | < 0.01 | 0.01 | [-0.01, 0.02] | 0.8210 |
Urinary disease (yes) | -0.02 | 0.01 | [-0.04, 0.00] | 0.0242 | <-0.01 | 0.01 | [-0.02, 0.01] | 0.5832 |
Allergies or Drug Sensitivities (yes) | <-0.01 | 0.01 | [-0.03, 0.02] | 0.7050 | -0.01 | 0.01 | [-0.03, 0.00] | 0.1582 |
Major Surgical Procedures (yes) | 0.02 | 0.01 | [0.00, 0.04] | 0.0510 | 0.02 | 0.01 | [0.00, 0.04] | 0.0350 |
Parkinsonism (yes) | -0.03 | 0.01 | [-0.06, -0.01] | 0.0115 | -0.02 | 0.01 | [-0.05, 0.01] | 0.1168 |
Geriatric Depression Scale | -0.03 | 0.01 | [-0.05, -0.01] | 0.0029 | -0.03 | 0.01 | [-0.04, -0.01] | 0.0005 |
Hachinski ischemic Scores | -0.01 | 0.01 | [-0.03, 0.01] | 0.2119 | < 0.01 | 0.01 | [-0.02, 0.02] | 0.8309 |