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Table 4 Multivariate Cox regression analysis of risk factors for cognitive diagnostic conversion

From: Risk factors for cognitive decline in non-demented elders with amyloid-beta positivity

Factors

HR

β

95%CI

p

Body weight (kg)

0.99

-0.01

[0.98, 1.01]

0.4328

BMI (≥ 25 kg/m2)

0.95

-0.05

[0.60, 1.51]

0.8382

Race (ref: White)

 Asian (yes)

0.84

-0.17

[0.30, 2.40]

0.7516

 Black (yes)

1.01

0.01

[0.24, 4.29]

0.9909

 More than one (yes)

0.60

-0.50

[0.14, 2.60]

0.4981

Alcohol abuse (yes)

1.34

0.29

[0.59, 3.05]

0.4911

Marital Status (ref: Married)

 Divorced

0.91

-0.09

[0.49, 1.70]

0.7683

 Widowed

0.66

-0.42

[0.34, 1.26]

0.2030

Never married

0.81

-0.21

[0.31, 2.13]

0.6662

Retired (yes)

1.65

0.50

[0.91, 3.01]

0.0996

Stroke (yes)

1.48

0.39

[0.79, 2.78]

0.2232

Hepatic diseases (yes)

0.74

-0.31

[0.31, 1.73]

0.4819

Gastrointestinal diseases (yes)

0.78

-0.24

[0.54, 1.13]

0.1912

Parkinsonism (yes)

6.55

1.88

[1.80, 23.91]

0.0044

Geriatric Depression Scale

2.381

0.87

[1.58, 3.60]

< 0.0001

  1. Bold indicated that the results were statistically significant (*p < 0.05)
  2. The age, gender, years of education, apolipoprotein Eε4 status, and baseline cognitive status were included as basic covariates
  3. Abbreviations: HR, hazard ratio; β, regression coefficient; 95%CI, 95% Confidence Interval; BMI, body mass index (calculated as weight in kilograms divided by square of height in meters); kg, kilogram; cm, centimeter; kg/m2, kilograms per square meter; mmHg, millimeters of mercury