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Table 3 Subgroup analysis for the associations between glycemic status and risk of all-cause mortality in individuals with dementia

From: Association between glycemic status and all-cause mortality among individuals with dementia: a nationwide cohort study

Subgroup

Normoglycemia

Prediabetes*

New-onset DM*

DM < 5 years*

DM ≥ 5 years*

P for

interaction

All-cause dementia

      

Age (years)

     

< 0.001

 40–64

1 (reference)

1.13 (1.02–1.25)

1.96 (1.67–2.30)

1.45 (1.27–1.66)

1.77 (1.60–1.96)

 

 ≥ 65

1 (reference)

1.02 (1.00–1.05)

1.32 (1.28–1.37)

1.15 (1.11–1.20)

1.42 (1.39–1.46)

 

Sex

     

0.052

 Men

1 (reference)

1.02 (0.98–1.05)

1.28 (1.21–1.36)

1.20 (1.14–1.27)

1.41 (1.36–1.46)

 

 Women

1 (reference)

1.04 (1.01–1.07)

1.39 (1.33–1.46)

1.14 (1.08–1.20)

1.45 (1.40–1.50)

 

Alzheimer’s disease

      

Age (years)

     

< 0.001

 40–64

1 (reference)

1.13 (0.99–1.29)

2.03 (1.66–2.49)

1.56 (1.31–1.86)

1.79 (1.57–2.04)

 

 ≥ 65

1 (reference)

1.02 (1.00–1.05)

1.32 (1.26–1.38)

1.16 (1.11–1.22)

1.42 (1.38–1.46)

 

Sex

     

0.172

 Men

1 (reference)

1.00 (0.96–1.04)

1.29 (1.20–1.38)

1.19 (1.11–1.27)

1.38 (1.32–1.45)

 

 Women

1 (reference)

1.05 (1.01–1.08)

1.37 (1.30–1.45)

1.17 (1.10–1.24)

1.46 (1.40–1.51)

 

Vascular dementia

      

Age (years)

     

0.150

 40–64

1 (reference)

1.04 (0.82–1.30)

1.81 (1.24–2.63)

1.33 (0.99–1.78)

1.91 (1.54–2.37)

 

 ≥ 65

1 (reference)

1.06 (0.99–1.13)

1.42 (1.28–1.59)

1.15 (1.03–1.28)

1.49 (1.39–1.60)

 

Sex

     

0.041

 Men

1 (reference)

1.14 (1.03–1.25)

1.31 (1.12–1.53)

1.22 (1.06–1.40)

1.55 (1.41–1.71)

 

 Women

1 (reference)

0.99 (0.90–1.09)

1.59 (1.38–1.82)

1.11 (0.95–1.29)

1.49 (1.36–1.63)

 
  1. Abbreviations: HR, hazard ratio; CI, confidence interval; DM, diabetes mellitus.
  2. *HRs (95% CIs) were calculated using a multivariable Cox hazards regression model adjusted for age, sex, place of residence, income, smoking status, alcohol consumption, physical activity, body mass index, hypertension, dyslipidemia, chronic kidney disease, disability, and number of anti-dementia medication