Fig. 11
From: Mitigation of synaptic and memory impairments via F-actin stabilization in Alzheimer’s disease
Disrupted PSD-95 actin association in human AD patients. (a, b) Representative immunoblot and quantification showing decreased PSD-95 actin association in MCI and AD patients compared with NCI. Statistical comparison between groups were conducted using one-way ANOVA on ranks followed by Dunn’s multiple comparison test. Data are presented as mean ± SEM (n = 10). Correlation analysis of PSD-95 actin association in human subjects with respect to cognitive performance (c), Braak score (d), amyloid-β deposition (e) tau tangle pathology (f) (n = 30, 10 from each group). Statistical significance: *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001