Fig. 5
From: Mitigation of synaptic and memory impairments via F-actin stabilization in Alzheimer’s disease
Altered PSD-95 association with AMPA and NMDA receptors in APP/PS1 mice. PSD-95 association with GluA1 (a-b) and GluA2 (c-d) in middle-aged APP/PS1 mice (n = 8). PSD-95 association with GluN1 in one-month- (e-f) and in nine-month-old APP/PS1 mice (g-h) (n = 8). PSD-95 association with GluN2A in one-month-(i-j) and in nine-month-old APP/PS1 mice (k-l) (n = 8). PSD-95 association with GluN2B in one-month- (m-n) and in nine-month-old APP/PS1 mice (o-p) (n = 8). Statistical comparison between groups was conducted using an unpaired two-tailed t-test. Data are presented as mean ± SEM. Statistical significance: *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001