Fig. 2
From: Different associations between body mass index and Alzheimer’s markers depending on metabolic health

Effect of metabolic health on the association between BMI status and Aβ positivity and severe WMH. (A) The risk of Aβ positivity increased in the underweight group but decreased in obesity group. Obesity decreased the risk of Aβ positivity in the MH group. Obesity did not increase the risk of Aβ positivity in the MU group. There was an interaction between obesity and metabolic health on Aβ positivity. (B) Obesity was associated with a higher risk of severe WMH. No significant interaction was observed between obesity and metabolic health on severe WMH. BMI = body mass index; MH = metabolically healthy; MU = metabolically unhealthy; WMH = white matter hyperintensity