Table 1 Descriptive statistics of the characteristics of participants included in this study (n = 10,062)
| Â | NACC participants (free of dementia at baseline) | No dementia development during follow-up | Dementia development during follow-up |
|---|---|---|---|
No. of participants | 10,062 | 9133 | 929 |
Sociodemographic | |||
Age, years, mean(sd) | 74.9(7.0) | 74.5 (6.8) | 79.1(7.0) |
Age, ≥ 80 years | 2619 (26.0) | 2173 (23.8) | 446(48.0) |
Sex, male % | 3570 (35.5) | 3237(35.4) | 333(35.8) |
Educational level, ≥ college education | 6390 (63.5) | 5838 (63.9) | 552(59.4) |
Hispanic/Latino ethnicity | 559 (5.6) | 522(5.7) | 37(4.0) |
Race, Black | 1429 (14.2) | 1334(14.6) | 95(10.2) |
Family history of dementia | 5165 (51.3) | 4636(50.8) | 529(56.9) |
APOE4 carrier | 2546 (25.3) | 2215(24.3) | 331(35.6) |
Health Behaviors | |||
Current smoking | 341 (3.4) | 308(3.4) | 33(3.6) |
Alcohol use disorder | 37 (0.4) | 32(0.4) | 5(0.5) |
Comorbidities | |||
Cardiovascular disease | 2537 (25.2) | 2276(24.9) | 261(28.1) |
Cerebrovascular disease | 661 (6.6) | 562(6.2) | 99(10.7) |
Neurological diseases | 777 (7.7) | 721(7.9) | 56(6.0) |
Neuropsychiatric disorders | 2555 (25.4) | 2323(25.4) | 232(25.0) |
Diabetes | 1212 (12.1) | 1108(12.1) | 104(11.2) |
Hypercholesterolemia | 5156 (51.2) | 4713(51.6) | 443(47.7) |
Hypertension | 5271 (52.4) | 4754(52.1) | 517(55.7) |
Obesity | 781 (23.3) | 2185(23.9) | 159(17.1) |