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Table 1 Schedule of the trial

From: TRanscranial AlterNating current stimulation FOR patients with mild Alzheimer’s Disease (TRANSFORM-AD): a randomized controlled clinical trial

 

Study period

Time point

Screening

Baseline

tACS

End of the intervention

3-month after randomization

Eligibility screen

X

 

↔

  

Informed consent

X

   

Randomization

 

X

  

Demographic data

 

X

  

Physical examination

 

X

X

X

Assessments

    

 CDR

X

 

X

X

 ADAS-cog

 

X

X

X

 MMSE

 

X

X

X

 MoCA

 

X

X

X

 AVLT

 

X

X

X

 Digit Span

 

X

X

X

 TMT

 

X

X

X

 BNT

 

X

X

X

 ADL

 

X

X

X

 NPI

 

X

X

X

 GDS.

 

X

X

X

MRI

 

X

X

X

EEG

 

X

X

X

PiB-PET or CSF Abeta42

X

   
  1. Abbreviations: CDR, Clinical Dementia Rating Scale; ADAS-cog, Cognitive subscale of the Alzheimer’s Disease Assessment Scale; MMSE, Mini-Mental State Examination; MoCA, Montreal Cognitive Assessment; AVLT, Auditory Verbal Learning Test; TMT, Trail Making Test; BNT, Boston Naming Test; ADL, Activities of Daily Living; NPI, Neuropsychiatric Inventory; GDS, Geriatric Depression Scale
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Alzheimer's Research & Therapy

ISSN: 1758-9193