Table 2 Baseline characteristics of the two groups
Variable | tACS group (n = 23) | Sham group (n = 23) | P value |
|---|---|---|---|
Age, y | 65.87 ± 5.21 (56–74) | 63.70 ± 6.05 (51–73) | 0.198 |
Sex, Female | 16 (69.5%) | 14 (60.9%) | 0.536 |
Education, y | 10.43 ± 2.91 (6–16) | 10.09 ± 3.84 (6–18) | 0.731 |
ADAS-Cog | 18.22 ± 5.92 (10–32) | 17.30 ± 5.98 (9–30) | 0.606 |
MMSE | 19.43 ± 3.33 (13–26) | 20.78 ± 3.04 (17–26) | 0.159 |
MoCA | 14.52 ± 3.82 (7–24) | 15.74 ± 3.99 (10–24) | 0.297 |
WHO-UCLA AVLT | |||
Immediate recall | 14.78 ± 5.95 (5–29) | 14.83 ± 4.54 (7–21) | 0.978 |
Delayed recall | 1.04 ± 1.29 (0–3) | 1.00 ± 1.20 (0–3) | 0.907 |
Recognition | 6.09 ± 3.48 (0–13) | 5.65 ± 2.98 (1–12) | 0.651 |
Digit span forward | 7.00 ± 1.41 (5–10) | 7.39 ± 1.08 (5–9) | 0.297 |
Digit span backward | 3.66 ± 0.98(2–6) | 4.04 ± 1.29 (2–8) | 0.255 |
BNT | 20.83 ± 3.52 (15–29) | 20.74 ± 4.87 (7–28) | 0.945 |
TMT B-A | 111.70 ± 82.42 (0-249) | 107.13 ± 84.06 (6-263) | 0.853 |
ADL | 24.55 ± 3.23 (20–33) | 26.09 ± 4.43 (21–38) | 0.191 |
NPI | 4.17 ± 5.82 (0–26) | 8.87 ± 12.21 (0–24) | 0.280 |
GDS | 7.39 ± 4.92 (1–16) | 5.64 ± 4.63 (0–16) | 0.178 |
Amyloid test, n (%)* | |||
positive amyloid-PET | 14 (60.8%) | 13 (56.5%) | 0.765 |
decreased CSF Abeta42 | 15 (65.2%) | 17 (73.9%) | 0.522 |
CSF Abeta42 levels (pg/ml) | 411.53 ± 45.50 (336.89-489.57) | 428.91 ± 40.53 (346.36-502.11) | 0.262 |