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Fig. 3 | Alzheimer's Research & Therapy

Fig. 3

From: Brain Iron in signature regions relating to cognitive aging in older adults: the Taizhou Imaging Study

Fig. 3

Association between localized QSM and longitudinal domain-specific cognitive score changes. AB Trajectory plots illustrate the impact of baseline QSM on the change in longitudinal attention and visuospatial function. The annual rate of domain-specific cognitive decline was calculated for each individual and plotted against the baseline localized QSM values. Estimated cognitive trajectories with 95% confidence intervals (CIs) are displayed. The model is adjusted for sex, age, years of education, smoking, drinking, hypertension, diabetes, and hyperlipidemia, eTIV and cortical thickness of each ROI (Supplemental Table 7; Model 3). Abbreviations: AD = Alzheimer's disease; AG = Aging; QSM = quantitative susceptibility mapping

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