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Table 1 Baseline demographical, clinical and MRI characteristics of participants

From: Brain Iron in signature regions relating to cognitive aging in older adults: the Taizhou Imaging Study

 

Baseline

(n = 770)

Demographics

 Age, y

62.0 ± 4.93

 Male

327 (42.5)

 Education, y

5.35 ± 3.80

Cognition

 Baseline MMSE, score

26.0 (22.0, 28.0)

 Baseline MoCA, score

18.0 (13.0, 22.0)

 Follow-up MMSEa, score

25.0 (22.0, 27.0)

 Follow-up MoCAa, score

17.0 (13.0, 21.0)

 Follow-up timea, year

2.68 ± 0.39

Neuroimaging

 Cortical QSM

0.74 ± 0.78

 AG-specific signature QSM

2.02 ± 0.93

 AD signature QSM

1.26 ± 1.80

 Global atrophy

0.70 ± 0.04

 Gray matter atrophy

0.38 ± 0.02

  1. Data are mean ± SD, n (%), or median (interquartile range)
  2. Demographic information and clinical characteristics were compared using 2, Student t-test and Mann-Whitney U-test
  3. Abbreviations: AD Alzheimer's disease, AG Aging, MMSE Mini-Mental State Examination, MoCA Montreal Cognitive Assessment, QSM Quantitative susceptibility mapping
  4. aData were summarized in subjects who completed follow-up phase I and II (n = 219)
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Alzheimer's Research & Therapy

ISSN: 1758-9193