Table 1 Baseline characteristics of participants in the UK Biobank, the Atherosclerosis Risk in Communities study, and the Framingham Offspring Study
Variable | UKB (n = 295,823) | ARIC (n = 12,547) | FOS (n = 2,004) |
|---|---|---|---|
Age, y, mean (SD) | 56.3 (5.9) | 54.0 (5.7) | 53.9 (5.9) |
Female, No. (%) | 163,675 (55.3) | 6,831 (54.4) | 1,056 (52.7) |
White ethnicity, No. (%) | 280,816 (95.0) | 9,510 (75.8) | 1,984 (99.0) |
Tertiary education, No. (%) | 98,528 (33.3) | 5,747 (45.8) | 1,204 (60.1) |
TDI, No. (%) | |||
Quartile 1 (least deprived) | 76,712 (25.9) | NA | NA |
Quartile 2 | 74,883 (25.3) | NA | NA |
Quartile 3 | 74,221 (25.1) | NA | NA |
Quartile 4 (most deprived) | 70,007 (23.7) | NA | NA |
Household income, No. (%) | |||
< 25,000 $ | NA | 4,459 (35.5) | 321 (16.0) |
25,000–49,999 $ | NA | 4,782 (38.1) | 1,002 (50.0) |
≥ 50,000 $ | NA | 3,306 (26.3) | 681 (34.0) |
Smoking status, No. (%) | |||
Never smokers | 30,919 (10.5) | 5,332 (42.5) | 677 (33.8) |
Former smokers | 100,541 (34.0) | 4,021 (32.0) | 871 (43.5) |
Current smokers | 164,363 (55.6) | 3,194 (25.5) | 456 (22.8) |
Alcohol intake, units/week, mean (SD) | 3.0 (3.3) | 3.2 (7.1) | 3.4 (5.0) |
BMI, kg/m2, mean (SD) | 27.5 (4.8) | 27.5 (5.1) | 27.1 (4.6) |
WC, cm, mean (SD) | 90.2 (13.4) | 96.6 (13.5) | 90.2 (14.3) |
SBP, mmHg, mean (SD) | 139.7 (19.2) | 120.8 (18.5) | 128.4 (17.5) |
DBP, mmHg, mean (SD) | 82.8 (10.6) | 73.6 (11.1) | 80.1 (9.6) |
HbA1c, mmol/mol, mean (SD) | 36.1 (6.6) | NA | NA |
FBG, mg/dL, mean (SD) | NA | 105.6 (32.5) | 96.4 (25.9) |
TG, mg/dL, mean (SD) | 155.9 (91.4) | 129.6 (88.7) | 129.5 (105.8) |
HDL-C, mg/dL, mean (SD) | 56.7 (14.8) | 51.9 (17.0) | 50.3 (15.4) |