Table 2 MVMR results of the causal association between genetically predicted hearing loss and dementia
Adjustment | CHL on AD | CSHL on DLB | CSHL on FTD | |||
|---|---|---|---|---|---|---|
OR (95% CI) | p-value | OR (95% CI) | p-value | OR (95% CI) | p-value | |
None | 1.07 (1.01, 1.14) | 0.031 | 1.69 (1.08, 2.63) | 0.021 | 1.66 (1.04, 2.67) | 0.035 |
Aging | 1.06 (1.00, 1.12) | 0.040 | 1.70 (0.98, 2.95) | 0.058 | 1.66 (1.29, 2.14) | < 0.001 |
Ischemic stroke | 1.07 (1.01, 1.14) | 0.024 | 1.80 (1.06, 3.03) | 0.028 | 1.76 (1.19, 2.57) | 0.004 |
Loneliness | 0.74 (0.51, 1.09) | 0.131 | 0.75 (0.22, 2.50) | 0.638 | 1.59 (0.55, 4.55) | 0.390 |
Depressed mood | 1.07 (1.02, 1.14) | 0.010 | 1.43 (0.84, 2.43) | 0.187 | 1.63 (0.92, 2.88) | 0.096 |
Cortical volume | 1.04 (0.96, 1.12) | 0.363 | 1.44 (0.92, 2.25) | 0.111 | 1.23 (0.75, 2.01) | 0.413 |