Fig. 1

Cognitive deficits and anxiety increased in AD mice. (A) Open field arena, (B) Morris Water Maze test, and (C) Y Maze, which were behavioral evaluation related to cognition and anxiety of 5×FAD mice. (A) Line at mean, floating from min to max. (B, C) values were expressed as mean ± SEM. WT-M: n = 16; Tg-M: n = 16; Tg-ABX: n = 10; Tg-F: n = 11. Differences were analyzed by Two-tested Student’s t test and donated as follows: *p < 0.05, **p < 0.01, ***p < 0.001