Fig. 4

Alterations in gut microbial diversity. (A) Diversity of fecal microbiota, including shannon, chao, coverage index. (B) PLS-DA plot. (C) BugBase phenotype prediction analysis. (D) Bacterias at phylum, (E) genus and family with relative abundance greater than 0.001%, red mean: Tg-M/WT-M > 1.5; blue mean: Tg-M/WT-M < 1.5. (A) Line at mean, floating from min to max. n = 9–11. Differences were analyzed by Two-tested Student’s t test and donated as follows: *p < 0.05, **p < 0.01, ***p < 0.001